Association of the Lewis genotype with cardiovascular risk factors and subclinical carotid atherosclerosis: the Atherosclerosis Risk in Communities (ARIC) study

Cakir B., Heiss G., Pankow J., Salomaa V., Sharrett A., Couper D., ...More

JOURNAL OF INTERNAL MEDICINE, vol.255, no.1, pp.40-51, 2004 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 255 Issue: 1
  • Publication Date: 2004
  • Doi Number: 10.1046/j.1365-2796.2003.01263.x
  • Journal Name: JOURNAL OF INTERNAL MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.40-51
  • Hacettepe University Affiliated: Yes

Abstract

Objectives. To evaluate the relationship of Lewis genotypes with major cardiovascular risk factors and the intima-media thickness (IMT) of carotid arteries. Lewis genotyping included four major mutations of the Lewis (FUT3) gene at nucleotide positions 59, 1067, 202 and 314.