Uterine tumors resembling ovarian sex cord-stromal tumors: synchronous uterine tumors resembling ovarian sex cord-stromal tumors and ovarian sex cord tumor

Abdullazade S., Kosemehmetoglu K., Adanir I., Kutluay L., USUBÜTÜN A.

ANNALS OF DIAGNOSTIC PATHOLOGY, cilt.14, sa.6, ss.432-437, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 6
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1016/j.anndiagpath.2010.07.001
  • Dergi Adı: ANNALS OF DIAGNOSTIC PATHOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.432-437
  • Anahtar Kelimeler: Uterus, UTROSCT, Granulosa cell tumor, Immunohistochemistry, CONSERVATIVE-MANAGEMENT, NEOPLASMS, DIFFERENTIATION, INHIBIN, MARKER
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Uterine tumors resembling ovarian sex cord-stromal tumors (UTROSCTs) are very rare. In this article, we present 3 cases that manifest classical histomorphological features alongside diverse immunohistochemical findings. As a distinctive finding, one of the patients had UTROSCT in the uterus and an ovarian sex cord tumor, called granulosa cell tumor, in the left ovary, simultaneously. Problems in diagnosing such pathologic condition generally arise because of the variable histologic picture of UTROSCT and may cause problems for general and other nongynecologic surgical pathologists. Immunohistochemically, these tumors express different markers that indicate their polyphenotypic origins. (C) 2010 Elsevier Inc. All rights reserved.