High-grade Atrioventricular Block Due to Lacosamide and Tizanidine Combination Therapy for Epilepsy and Multiple Sclerosis


Kılıç S., Canpolat U.

Acta Medica, vol.54, no.1, pp.83-87, 2022 (Peer-Reviewed Journal)

  • Publication Type: Article / Article
  • Volume: 54 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.32552/2022.actamedica.779
  • Journal Name: Acta Medica
  • Journal Indexes: TR DİZİN (ULAKBİM)
  • Page Numbers: pp.83-87
  • Hacettepe University Affiliated: Yes

Abstract

Drug-induced atrioventricular (AV) block can be caused by cardiac and non-cardiac medications. The clinical condition may be temporary, persistent, or recurrent. However, there is no standard approach for management and follow-up of patients with drug-induced AV block. Herein, we presented a patient with the diagnosis of epilepsy and multiple sclerosis who admitted to emergency room with epileptic seizure. Temporary advanced AV block was observed on admission and during in-hospital follow-up which was thought to be caused by lacosamide and tizanidine medications and improved after drug discontinuation.