First report of t(1;15)(q21;q11.2) and t(1;21)(q21;q11.2) anomalies in Burkitt Lymphoma

Bozkurt S., OKAY M., Haznedaroglu C. I.

KUWAIT MEDICAL JOURNAL, vol.53, no.3, pp.344-345, 2021 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 3
  • Publication Date: 2021
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), EMBASE
  • Page Numbers: pp.344-345
  • Keywords: cytogenetic, rare chromosomal anomalies, rare translocations
  • Hacettepe University Affiliated: Yes


Burkitt lymphoma (BL) is a highly aggressive B cell neoplasm characterized by t(8;14)(q24;q32) which involves the MYC gene. Sometimes, patients have additional cytogenetic anomalies beside t(8;14)(q24;q32) and these anomalies usually lead to more aggressive phenotype. The aim of this paper is to report two novel karyotypic abnormalities which give rise to tetrasomy 1q with an aggressive clinical course of BL.