First report of t(1;15)(q21;q11.2) and t(1;21)(q21;q11.2) anomalies in Burkitt Lymphoma
KUWAIT MEDICAL JOURNAL, cilt.53, sa.3, ss.344-345, 2021 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 53 Sayı: 3
- Basım Tarihi: 2021
- Dergi Adı: KUWAIT MEDICAL JOURNAL
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), EMBASE
- Sayfa Sayıları: ss.344-345
- Anahtar Kelimeler: cytogenetic, rare chromosomal anomalies, rare translocations
- Hacettepe Üniversitesi Adresli: Evet
Özet
Burkitt lymphoma (BL) is a highly aggressive B cell neoplasm characterized by t(8;14)(q24;q32) which involves the MYC gene. Sometimes, patients have additional cytogenetic anomalies beside t(8;14)(q24;q32) and these anomalies usually lead to more aggressive phenotype. The aim of this paper is to report two novel karyotypic abnormalities which give rise to tetrasomy 1q with an aggressive clinical course of BL.