Atypical teratoid/rhabdoid tumors: Imaging gindings of two cases and review of the literature


Tez S., Koktener A., GÜLER G., Ozisik P.

TURKISH NEUROSURGERY, vol.18, no.1, pp.30-34, 2008 (Peer-Reviewed Journal) identifier

  • Publication Type: Article / Review
  • Volume: 18 Issue: 1
  • Publication Date: 2008
  • Journal Name: TURKISH NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.30-34

Abstract

Atypical teratoid/rhabdoid tumor (AT/RT) is a malignant embryonal central nervous system (CNS) tumor, manifesting in children, and composed of rhabdoid cells, with or without fields resembling a classical primitive neuroectodermal tumor (PNET), epithelial tissue and neoplastic mesenchyme. Around 200 cases of CNS AT/RT have been documented in the literature. Although the clinical and pathological findings have been defined in large series previously, and AT/RT has become increasingly recognized, awareness of typical AT/RT is important in making the correct diagnosis of this uncommon but probably underdiagnosed entity. Neuroradiologists rarely mention AT/RT in their differential diagnosis and this paper presents two additional cases in which clinical and pathological findings are combined with neuroradiological presentation.