Current and future systemic treatment options in metastatic pancreatic cancer
JOURNAL OF GASTROINTESTINAL ONCOLOGY, cilt.5, sa.4, ss.280-295, 2014 (ESCI, Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 5 Sayı: 4
- Basım Tarihi: 2014
- Doi Numarası: 10.3978/j.issn.2078-6891.2014.030
- Dergi Adı: JOURNAL OF GASTROINTESTINAL ONCOLOGY
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
- Sayfa Sayıları: ss.280-295
- Hacettepe Üniversitesi Adresli: Evet
Özet
Although pancreatic adenocarcinoma is the fourth leading cause of cancer death, only modest improvement has been observed in the past two decades, single agent gemcitabine has been the only standard treatment in patients with advanced disease. Recently newer agents such as nab-paclitaxel, nimotuzumab and regimens such as FOLFIRINOX have been shown to have promising activity being superior to gemcitabine as a single agent. With better understanding of tumour biology coupled with the improvements in targeted and immunotherapies, there is increasing expectation for better response rates and extended survival in pancreatic cancer.