Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: a microSOAP post hoc analysis


Vellinga N. A. R. , Boerma E. C. , Koopmans M., Donati A., Dubin A., Shapiro N. I. , ...Daha Fazla

CRITICAL CARE, cilt.21, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Background: Mildly elevated lactate levels (i.e., 1-2 mmol/L) are increasingly recognized as a prognostic finding in critically ill patients. One of several possible underlying mechanisms, microcirculatory dysfunction, can be assessed at the bedside using sublingual direct in vivo microscopy. We aimed to evaluate the association between relative hyperlactatemia, microcirculatory flow, and outcome.