Glomerulonephritis with crescents in childhood; etiologies and significance of M2 macrophages


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KAYKI G., ORHAN D., GÜLHAN B., TOPALOĞLU R., AKÇÖREN Z., DÜZOVA A., ...More

TURKISH JOURNAL OF PEDIATRICS, vol.64, no.1, pp.59-68, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 64 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.24953/turkjped.2020.2172
  • Journal Name: TURKISH JOURNAL OF PEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.59-68
  • Keywords: crescentic glomerulonephritis, CD163 macrophages, M2 macrophages, IGA NEPHROPATHY, SINGLE-CENTER, CHILDREN, PURPURA, DISEASE, INJURY
  • Hacettepe University Affiliated: Yes

Abstract

Background. Crescentic glomerulonephritis (CGN) is a rapidly progressive and rare cause of glomerulonephritis in childhood. The aim of this study is to evaluate demographic data of children with crescentic glomerulonephritis, to classify the etiologies and to investigate the correlation between the severity of kidney disease and the expression of CD163+ macrophages.