Environmental boron exposure does not induce DNA damage in lymphocytes and buccal cells of females DNA damage in lymphocytes and buccal cells of boron exposed females

Basaran N., Duydu Y., Ustundag A., Taner G., AYDIN DİLSİZ S., Anlar H. G., ...Daha Fazla

JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY, cilt.53, ss.150-153, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.jtemb.2019.03.004
  • Dergi Adı: JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.150-153
  • Anahtar Kelimeler: Boric acid, Boron exposure, DNA damage, BORIC-ACID, DIETARY BORON, GENOTOXICITY, BORAX, ASSAY
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Boron (B) compounds are essential for plants and animals and beneficial for humans in nutritional amounts. I animals and humans increasing evidence have shown beneficial effects on B compounds on nutrition and on antioxidant status. The genotoxic effects of environmental B exposure in women living in boron-rich and boronpoor areas was examined in this study. For this purpose, the DNA damage in the lymphocytes and buccal cells of females were assessed by Comet and micronucleus (MN) assays respectively. No significant difference was observed in the DNA damage of the lymphocytes of B exposed groups of female volunteers in Comet assay. Even buccal micronucleus (MN) frequency observed in the high exposure group was significantly lower than the low exposure group (p < 0.05). The results of this study came to the same conclusions of the previous studies that boron does not induce DNA damage even under extreme exposure conditions.