Addition of intramuscular progesterone to vaginal progesterone in hormone replacement therapy in vitrified-warmed blastocyst transfer cycles

Polat, Mehtap; MÜMÜŞOĞLU, SEZCAN; BOZDAĞ, GÜRKAN; Ozbek, Irem; Humaidan, Peter; Yarali, Hakan

doi:10.1016/j.rbmo.2020.01.0311472-6483

Addition of intramuscular progesterone to vaginal progesterone in hormone replacement therapy in vitrified-warmed blastocyst transfer cycles

Polat M., MÜMÜŞOĞLU S., BOZDAĞ G., Ozbek I. Y., Humaidan P., Yarali H.

REPRODUCTIVE BIOMEDICINE ONLINE, vol.40, no.6, pp.812-818, 2020 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 40 Issue: 6
Publication Date: 2020
Doi Number: 10.1016/j.rbmo.2020.01.0311472-6483
Journal Name: REPRODUCTIVE BIOMEDICINE ONLINE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
Page Numbers: pp.812-818
Keywords: Cryopreserved embryo transfer, Hormone replacement therapy, Im progesterone supplementation, IVF, Serum progesterone, Vaginal progesterone supplementation, SERUM PROGESTERONE, EMBRYO-TRANSFER, IMPLANTATION, ENDOMETRIN, RATES
Hacettepe University Affiliated: Yes

Abstract

Research question: Does intramuscular progesterone supplementation ensure ongoing pregnancy rates (OPR) comparable with vaginal progesterone only in hormone replacement therapy cycles for vitrified-warmed embryo transfer; and is there a window of serum progesterone concentration out of which reproductive outcomes may be negatively affected?