Magnesium sulfate treatment decreases caspase-3 activity after experimental spinal cord injury in rats
SURGICAL NEUROLOGY, cilt.64, ss.17-21, 2005 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 64
- Basım Tarihi: 2005
- Doi Numarası: 10.1016/j.surneu.2005.07.058
- Dergi Adı: SURGICAL NEUROLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.17-21
- Hacettepe Üniversitesi Adresli: Hayır
Özet
Background: Apoptosis has increasingly been considered as an important factor in secondary injury after spinal cord injury (SCI). Manifestation of apoptotic cell death process involves activation of the caspase-3 apoptotic cascade. The aim of the study was to demonstrate the effect of magnesium sulfate on caspase-3 activity and to compare its effectiveness with methylprednisolone after acute SCI.