The COVID-19 Pandemic and Enzyme Replacement Therapy in Lysosomal Storage Disorders

Olgaci A., KASAPKARA Ç. S. , Acikel B., Yildiz Y., Molla G. K. , Kilic M.

JOURNAL OF PEDIATRIC RESEARCH, vol.8, no.4, pp.370-376, 2021 (Peer-Reviewed Journal) identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 4
  • Publication Date: 2021
  • Doi Number: 10.4274/jpr.galenos.2020.98250
  • Journal Indexes: Emerging Sources Citation Index, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.370-376
  • Keywords: COVID-19, lysosomal storage disease, enzyme replacement therapy, home-therapy, REVISED CHILD ANXIETY, PSYCHOMETRIC PROPERTIES, DEPRESSION SCALE, DISEASE, VERSION


Aim: The coronavirus disease-2019 (COVID-19) pandemic has caused a worldwide public health emergency, especially affecting people with chronic illnesses including lysosomal storage disorders (LSDs). The unfavorable conditions due to COVID-19 have mostly affected people with chronic conditions, in terms of disease vulnerability and access to health-care. In the present study, we aimed to assess the problems the patients with LSDs on enzyme replacement therapy (ERT) have encountered during the pandemic, and their level of anxiety. Parental evaluation has also been made for pediatric patients.