Deciduous Tooth Pulp Autotransplantation for the Regenerative Endodontic Treatment of Permanent Teeth With Pulp Necrosis: A Case Series


ÇEHRELİ Z. C., ERBAŞ ÜNVERDİ G., BALLIKAYA E.

JOURNAL OF ENDODONTICS, vol.48, no.5, pp.669-674, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 5
  • Publication Date: 2022
  • Doi Number: 10.1016/j.joen.2022.01.015
  • Journal Name: JOURNAL OF ENDODONTICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.669-674
  • Keywords: Autologous transplantation, deciduous tooth, pulp, regeneration, regenerative endodontics, revascularization, MESENCHYMAL STEM-CELLS, APICAL PERIODONTITIS, TREATMENT REVASCULARIZATION, CALCIUM HYDROXIDE, NECROTIC PULPS, IMMATURE TEETH, DELIVERY, MOLARS
  • Hacettepe University Affiliated: Yes

Abstract

Introduction: In young individuals, deciduous tooth pulp might be used as a natural, biologic scaffold for the regenerative endodontic treatment (RET) of young permanent teeth with necrotic pulps and apical periodontitis. The present case series demonstrates the clinical and radiographic outcomes of a novel RET using deciduous pulp autotransplantation in traumatized, necrotic young permanent incisors. Methods: Five previously traumatized maxillary incisors of four 8-to 11.5-year-old patients were treated with a RET protocol that used 2.5% NaOCl irrigation and placement of calcium hydroxide dressing in the first visit. After 4 weeks, the intracanal medication was removed, and the whole pulp tissue harvested from the neighboring maxillary deciduous canine was transplanted into the disinfected root canal without induced apical bleeding. Following placement of a mineral trioxide aggregate coronal barrier, the access cavities were restored with acid-etch resin composite. The root canals of donor primary canines were filled with calcium hydroxide-iodoform paste and were restored as with the permanent incisors. Results: Three patients were followed-up for 24 months, and 1 patient for 12 months. All teeth demonstrated radiographic evidence of complete periapical healing, slight increase in dentinal wall thickness, and continued apical closure in the absence of clinical symptoms. A positive response to cold test was obtained in 1 incisor at 12 months and 2 at 24 months. Conclusions: Based on 12-and 24-month clinical and radiographic findings, the present cases demonstrate a favorable outcome of a RET protocol using de-ciduous pulp autotransplantation in young permanent incisors with pulp necrosis. (J Endod 2022;48:669-674.)