THE EFFECT OF ANTIOXIDANTS ON BLEOMYCIN TREATMENT IN IN-VITRO AND IN-VIVO GENOTOXICITY ASSAYS

ANDERSON D., BASARAN N., BLOWERS S., EDWARDS A.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, cilt.329, sa.1, ss.37-47, 1995 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 329 Sayı: 1
  • Basım Tarihi: 1995
  • Doi Numarası: 10.1016/0027-5107(95)00017-d
  • Dergi Adı: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chimica, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.37-47
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Antioxidants are thought to be important in protecting against damage from active oxygen species. The effects of the antioxidant nutrients vitamins C and E have been investigated after bleomycin treatment in the Salmonella typhimurium bacterial mutation assay, in the human peripheral lymphocyte chromosome aberration assay, and in the mouse micronucleus assay in peripheral blood and bone marrow cells.