THE EFFECT OF ANTIOXIDANTS ON BLEOMYCIN TREATMENT IN IN-VITRO AND IN-VIVO GENOTOXICITY ASSAYS


ANDERSON D. , BASARAN N., BLOWERS S., EDWARDS A.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, cilt.329, ss.37-47, 1995 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 329 Konu: 1
  • Basım Tarihi: 1995
  • Doi Numarası: 10.1016/0027-5107(95)00017-d
  • Dergi Adı: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
  • Sayfa Sayıları: ss.37-47

Özet

Antioxidants are thought to be important in protecting against damage from active oxygen species. The effects of the antioxidant nutrients vitamins C and E have been investigated after bleomycin treatment in the Salmonella typhimurium bacterial mutation assay, in the human peripheral lymphocyte chromosome aberration assay, and in the mouse micronucleus assay in peripheral blood and bone marrow cells.