THE EFFECT OF ANTIOXIDANTS ON BLEOMYCIN TREATMENT IN IN-VITRO AND IN-VIVO GENOTOXICITY ASSAYS


ANDERSON D., BASARAN N., BLOWERS S., EDWARDS A.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, vol.329, no.1, pp.37-47, 1995 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 329 Issue: 1
  • Publication Date: 1995
  • Doi Number: 10.1016/0027-5107(95)00017-d
  • Journal Name: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
  • Journal Indexes: Science Citation Index Expanded, Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chimica, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.37-47

Abstract

Antioxidants are thought to be important in protecting against damage from active oxygen species. The effects of the antioxidant nutrients vitamins C and E have been investigated after bleomycin treatment in the Salmonella typhimurium bacterial mutation assay, in the human peripheral lymphocyte chromosome aberration assay, and in the mouse micronucleus assay in peripheral blood and bone marrow cells.