Multi-institutional evaluation of the prognostic significance of EZH2 expression in high-grade upper tract urothelial carcinoma

Singla, Nirmish; Krabbe, Laura-Maria; Aydin, Ahmet; Panwar, Vandana; Woldu, Solomon; Freifeld, Yuval; Wood, Christopher; Karam, Jose; Weizer, Alon; Raman, Jay; Remzi, Mesut; Rioux-Leclercq, Nathalie; Haitel, Andrea; Roscigno, Marco; Bolenz, Christian; Bensalah, Karim; Sagalowsky, Arthur; Shariat, Shahrokh; Lotan, Yair; Bagrodia, Aditya; Kapur, Payal; Margulis, Vitaly

doi:10.1016/j.urolonc.2018.04.004

Multi-institutional evaluation of the prognostic significance of EZH2 expression in high-grade upper tract urothelial carcinoma

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Singla N., Krabbe L., Aydin A. M., Panwar V., Woldu S. L., Freifeld Y., ...More

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, vol.36, no.7, 2018 (SCI-Expanded)

Publication Type: Article / Article
Volume: 36 Issue: 7
Publication Date: 2018
Doi Number: 10.1016/j.urolonc.2018.04.004
Journal Name: UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Hacettepe University Affiliated: No

Abstract

Purpose: Enhancer of zeste homolog 2 is a methyltransferase encoded by the EZH2 gene, whose role in upper tract urothelial carcinoma (UTUC) is poorly understood. We sought to evaluate the prognostic value of EZH2 expression in UTUC.