Copy For Citation
Unaleroglu C., Temelli B., Demir A. s.
SYNTHESIS-STUTTGART, no.15, pp.2574-2578, 2004 (SCI-Expanded)
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Publication Type:
Article / Article
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Publication Date:
2004
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Doi Number:
10.1055/s-2004-831195
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Journal Name:
SYNTHESIS-STUTTGART
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.2574-2578
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Keywords:
homochiral pyrroles, metal triflates, conjugate addition, Friedel-Crafts reaction, pyrroles, INTRAMOLECULAR CARBENOID REACTIONS, DERIVATIVES, ALKYLATION, KETOESTERS
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Hacettepe University Affiliated:
Yes
Abstract
The Friedel-Crafts reaction of homochiral pyrrole derivatives with alpha,beta-unsaturated esters catalyzed by metal triflates furnished conjugate addition products. The best yields were obtained by using yttrium triflate and methyl 4-phenyl-2-oxobut-3-enoate (2a). The addition worked regioselectively at C-5 of pyrrole. The diastereoisomers were separated by column chromatography.