Multiple lentigines confined to psoriatic plaques induced by biologic agents in psoriasis therapy: a case and review of the literature


Dogan S. , Atakan N.

CUTANEOUS AND OCULAR TOXICOLOGY, cilt.34, ss.262-264, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 34 Konu: 3
  • Basım Tarihi: 2015
  • Doi Numarası: 10.3109/15569527.2014.959664
  • Dergi Adı: CUTANEOUS AND OCULAR TOXICOLOGY
  • Sayfa Sayıları: ss.262-264

Özet

Multiple lentigines confined to psoriatic plaques is a rare entity, which is more frequently recognized after the use of systemic biologic agents for psoriasis therapy. Although this phenomenon was previously accepted as a postinflammatory reaction, recent observations suggest psoriasis-related cytokines and their efficient supression by biologic agents strongly associate with melanogenesis and melanocytic proliferation. Hereby, we report a patient who developed multiple lentigines arising in resolved psoriatic plaques induced by infliximab and review similar cases reported in the literature induced after biologic treatments of psoriasis.