Morphologic and mechanical characteristics of engineered bovine arteries


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Niklason L., Abbott W., Gao J., Klagges B., Hirschi K., Ulubayram K., ...More

JOURNAL OF VASCULAR SURGERY, vol.33, no.3, pp.628-638, 2001 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 3
  • Publication Date: 2001
  • Doi Number: 10.1067/mva.2001.111747
  • Journal Name: JOURNAL OF VASCULAR SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.628-638
  • Hacettepe University Affiliated: Yes

Abstract

Objective: The ideal small-caliber arterial graft remains elusive despite several decades of intense research. A novel approach to the development of small-caliber arterial prostheses with a biomimetic system for in vitro vessel culture has recently been described. In this study we examined the effects of culture time and tissue culture scaffolding on engineered vessel morphology and function and found that these parameters greatly influence the function of engineered vessels.