The purpose of this study were to examine the relationship among physicians' and nurses' levels of organizational commitment, organizational trust and job satisfaction. This study was conducted at five The Republic of Turkey Ministery of Health training and education hospitals in Istanbul. In this study, 304 physicians (12,54% of total physicians) and 254 nurses (15,38% total nurses) responded to all questions in the instruments. 13,68% of universe was reached. The measurement instruments of survey are the Job Satisfaction Survey, the Organizational Commitment Questionnarie and Organizational Trust Inventory - short form. Seven point Likert scales are used in these measurement instruments. A strong positive correlations and relationships were found to exist among organizational commitment, organizational trust and job satisfaction. Regression analyses showed that organizational trust affect organizational commitment significantly. Also it was found that organizational trust affect job satisfaction significantly. The higher levels of organizational commitment and trust of physicians and nurses are associated with greater job satisfaction. Especially there are strong inference between organizational trust and job satisfaction, organizational trust and organizational commitment.