Thyrotropinoma and multinodular goiter: A diagnostic challenge for hyperthyroidism

Aksoy D. Y., Gedik A., Cinar N., Soylemezoglu F., BERKER M., GÜRLEK Ö. A.

JOURNAL OF RESEARCH IN MEDICAL SCIENCES, cilt.18, sa.11, ss.1008-1010, 2013 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 11
  • Basım Tarihi: 2013
  • Dergi Adı: JOURNAL OF RESEARCH IN MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1008-1010
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Thyroid disorders are frequently encountered. The diagnosis is straightforward unless clinical or laboratory findings are inconclusive and/or perplexing. Hyperthyroidism due to a thyrotropin-secreting pituitary adenoma rarely occurs and symptoms due to thyroid hormone excess are subtle. The presentation of the disease becomes unusual when co-secretion of other hormones with thyrotropin or concomitant thyroid parenchymal pathology exist. We present the case of a 63-year-old female patient with thyrotropinoma co-secreting growth hormone and multinodular goiter. She developed hyperthyroidism first due to thyrotropinoma and later due to a toxic nodule. Herein, we discuss the diagnostic and therapeutic challenges of hyperthyroidism with atypical presentation.