Inhibition of human glutathione transferase P1-1 by novel benzazole derivatives

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Atıf İçin Kopyala

Musdal Y., Ertan-Bolelli T., Bolelli K., Yilmaz S., Ceyhan D., Hegazy U., ...Daha Fazla

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.37, sa.4, ss.431-436, 2012 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 37 Sayı: 4
• Basım Tarihi: 2012
• Doi Numarası: 10.5505/tjb.2012.30301
• Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
• Sayfa Sayıları: ss.431-436
• Hacettepe Üniversitesi Adresli: Evet

Özet

Objective: Glutathione transferases (GST) are multifunctional enzymes involved in detoxication, drug resistance, cell signaling and apoptosis. The inhibitory effects of novel benzazole derivatives were tested on human GST P1-1 to find new agents for overcoming drug resistance in cancer cells.