CLINICAL PHARMACOLOGY & THERAPEUTICS, vol.76, no.2, pp.113-118, 2004 (Peer-Reviewed Journal)
Article / Article
CLINICAL PHARMACOLOGY & THERAPEUTICS
Science Citation Index Expanded, Scopus
Background and Aim: Previous data indicate that the urinary losartan/E-3174 ratio is a marker for cytochrome P450 (CYP) 2C9 activity in vivo. The functional impact of CYP2C9(star)5, (star)6, (star)8, and (star)11 polymorphisms in vivo has not been investigated previously in humans.