Association of Ugrp2 gene polymorphisms with adenoid hypertrophy in the pediatric population

Atilla, Mahmut; Ozdas, Sibel; Ozdas, Talih; Bastimur, Sibel; Muz, Sami; Oz, Isilay; Kurt, Kenan; İZBIRAK, AFİFE; Babademez, Mehmet; Vatandas, Nilgun

doi:10.1016/j.bjorl.2017.07.004

Association of Ugrp2 gene polymorphisms with adenoid hypertrophy in the pediatric population

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Atilla M. H. , Ozdas S., Ozdas T., Bastimur S., Muz S. E. , Oz I., ...More

BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY, vol.84, no.5, pp.599-607, 2018 (SCI-Expanded)

Publication Type: Article / Article
Volume: 84 Issue: 5
Publication Date: 2018
Doi Number: 10.1016/j.bjorl.2017.07.004
Journal Name: BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.599-607
Hacettepe University Affiliated: Yes

Abstract

Introduction: Adenoid hypertrophy is a condition that presents itself as the chronic enlargement of adenoid tissues; it is frequently observed in the pediatric population. The Ugrp2 gene, a member of the secretoglobin superfamily, encodes a low-molecular weight protein that functions in the differentiation of upper airway epithelial cells. However, little is known about the association of Ugrp2 genetic variations with adenoid hypertrophy.