Gingival crevicular fluid levels of human beta-defensin-1 in type 2 diabetes mellitus and periodontitis
CLINICAL ORAL INVESTIGATIONS, vol.22, no.5, pp.2135-2140, 2018 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 22 Issue: 5
- Publication Date: 2018
- Doi Number: 10.1007/s00784-018-2469-z
- Journal Name: CLINICAL ORAL INVESTIGATIONS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.2135-2140
- Keywords: Antimicrobial peptides, Diabetes mellitus, Periodontitis, Gingival crevicular fluid, GENE-EXPRESSION, DEFENSINS, GLUCOSE, HEALTH, HBD-2
- Hacettepe University Affiliated: Yes
Abstract
Objectives Human beta-defensin (hBD)-1 is an important gatekeeper of the gingiva against constant bacterial challenge, and glucose levels are involved in its optimal expression. The aims of the study were to investigate hBD-1 levels in gingival crevicular fluid (GCF) and to compare these levels between type 2 diabetics with or without periodontitis and healthy individuals.