Gingival crevicular fluid levels of human beta-defensin-1 in type 2 diabetes mellitus and periodontitis

Yilmaz, DOĞUKAN; Çağlayan, FERİHA; Büber, ESRA; Kononen, Eija; Aksoy, YASEMİN; Gursoy, Ulvi; Güncü, GÜLİZ

doi:10.1007/s00784-018-2469-z

Gingival crevicular fluid levels of human beta-defensin-1 in type 2 diabetes mellitus and periodontitis

Yilmaz D., Çağlayan F., Büber E., Kononen E., Aksoy Y., Gursoy U. K., ...Daha Fazla

CLINICAL ORAL INVESTIGATIONS, cilt.22, sa.5, ss.2135-2140, 2018 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 22 Sayı: 5
Basım Tarihi: 2018
Doi Numarası: 10.1007/s00784-018-2469-z
Dergi Adı: CLINICAL ORAL INVESTIGATIONS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.2135-2140
Anahtar Kelimeler: Antimicrobial peptides, Diabetes mellitus, Periodontitis, Gingival crevicular fluid, GENE-EXPRESSION, DEFENSINS, GLUCOSE, HEALTH, HBD-2
Hacettepe Üniversitesi Adresli: Evet

Özet

Objectives Human beta-defensin (hBD)-1 is an important gatekeeper of the gingiva against constant bacterial challenge, and glucose levels are involved in its optimal expression. The aims of the study were to investigate hBD-1 levels in gingival crevicular fluid (GCF) and to compare these levels between type 2 diabetics with or without periodontitis and healthy individuals.