Gingival crevicular fluid levels of human beta-defensin-1 in type 2 diabetes mellitus and periodontitis

Yilmaz D., ÇAĞLAYAN F., BÜBER E., Kononen E., AKSOY Y., Gursoy U. K., ...Daha Fazla

CLINICAL ORAL INVESTIGATIONS, cilt.22, sa.5, ss.2135-2140, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 5
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1007/s00784-018-2469-z
  • Dergi Adı: CLINICAL ORAL INVESTIGATIONS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2135-2140
  • Anahtar Kelimeler: Antimicrobial peptides, Diabetes mellitus, Periodontitis, Gingival crevicular fluid, GENE-EXPRESSION, DEFENSINS, GLUCOSE, HEALTH, HBD-2
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Objectives Human beta-defensin (hBD)-1 is an important gatekeeper of the gingiva against constant bacterial challenge, and glucose levels are involved in its optimal expression. The aims of the study were to investigate hBD-1 levels in gingival crevicular fluid (GCF) and to compare these levels between type 2 diabetics with or without periodontitis and healthy individuals.