Letrozole induces hepatotoxicity without causing oxidative stress: the protective effect of melatonin

Aydin M., Oktar S., Ozkan O. V., Alcin E., Ozturk O. H., Nacar A.

GYNECOLOGICAL ENDOCRINOLOGY, vol.27, no.4, pp.209-215, 2011 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 27 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.3109/09513590.2010.488769
  • Journal Name: GYNECOLOGICAL ENDOCRINOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.209-215
  • Hacettepe University Affiliated: No

Abstract

Aim. The aim of this study was to determine the effects of letrozole (LTZ), an aromatase inhibitor (AI), and melatonin (MLT) on hepatic function and oxidative stress in female rats.