Glucosides from Vitex agnus-castus


KURUUZUM-UZ A. , STROCH K., Demirezer L. Ö. , ZEECK A.

PHYTOCHEMISTRY, cilt.63, ss.959-964, 2003 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 63 Konu: 8
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1016/s0031-9422(03)00285-1
  • Dergi Adı: PHYTOCHEMISTRY
  • Sayfa Sayıları: ss.959-964

Özet

The methanolic extract of the flowering steins of Vitex agnus-castus yielded three new iridoids: 6'-O-foliamenthoylmussaenosidic acid (agnucastoside A), 6'-O-(6,7-dihydrofoliamenthoyl)mussaenosidic acid (agnucastoside B) and 7-O-trans-p-coumaroyl-6'-O-trans-caffeoyl-8-epiloganic acid (agnucastoside C) in addition to four known iridoids (aucubin, agnuside, mussaenosidic acid and 6'O-p-hydroxybenzoylmussaenosidic acid) and one known phenylbutanone glucoside (myzodendrone). The structure elucidations were mainly done by spectroscopic methods (1D and 2D NMR spectra) and MS data interpretation. The purified compounds were tested for biological activities against various microorganisms and cancer cell lilies. (C) 2003 Elsevier Ltd. All rights reserved.