Childhood Interstitial Lung Disease

Nayir Buyuksahin H., Kiper N.

Pediatric, Allergy, Immunology, and Pulmonology, vol.36, no.1, pp.5-15, 2023 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 36 Issue: 1
  • Publication Date: 2023
  • Doi Number: 10.1089/ped.2022.0013
  • Journal Name: Pediatric, Allergy, Immunology, and Pulmonology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.5-15
  • Keywords: children, interstitial, lung disease, computed tomography, genetic tests
  • Hacettepe University Affiliated: Yes

Abstract

Childhood interstitial lung disease (chILD) is a heterogeneous group of diseases with various clinical and imaging findings. The incidence and prevalence have increased in recent years, probably due to better comprehension of these rare diseases and increased awareness among physicians. chILDs present with nonspecific pulmonary symptoms, such as tachypnea, hypoxemia, cough, rales, and failure to thrive. Unnecessary invasive procedures can be avoided if specific mutations are detected through genetic examinations or if typical imaging patterns are recognized on computed tomography. Disease knowledge and targeted therapies are improving through international collaboration. Pulmonary involvement in systemic diseases is not uncommon. Pulmonary involvement may be the first finding in connective tissue diseases. This review aims to present a systematic patient-targeted approach to the diagnosis of chILD.