Comparison of Growth Hormone Receptor, IGF-1R and IGFBP-3 Between Tumoral and Non-Tumoral Areas in Non-Melanoma Skin Cancers


Gunduz O., GÖKÖZ Ö. , ERKİN ÖZAYGEN G. , Akan T.

TURKISH JOURNAL OF PATHOLOGY, cilt.29, ss.185-192, 2013 (ESCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 29 Konu: 3
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5146/tjpath.2013.01185
  • Dergi Adı: TURKISH JOURNAL OF PATHOLOGY
  • Sayfa Sayıları: ss.185-192

Özet

Objective: A relationship between the pathogenesis of some cancers and growth hormone, insulin-like growth factor-1 and insulin-like growth factors binding protein-3 has been shown. Our aim was to evaluate the expression of growth hormone receptor, insulin-like growth factor-1 receptor and insulin-like growth factors binding protein-3 in actinic keratosis, basal cell carcinoma and squamous cell carcinoma, and to compare the expression patterns of tumoral areas with normal epidermis and skin appendages.