Effects of local alendronate administration on bone defect healing. Histomorphometric and radiological evaluation in a rabbit model


Özer T., Aktaş A., Barış E., Çelik H. H. , Vatansever A.

ACTA CIRURGICA BRASILEIRA, vol.32, pp.781-795, 2017 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32
  • Publication Date: 2017
  • Doi Number: 10.1590/s0102-865020170090000010
  • Journal Name: ACTA CIRURGICA BRASILEIRA
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.781-795
  • Keywords: Alendronate, Disphosphonates, Bone Transplantation, Rabbits, BISPHOSPHONATE TREATMENT, INCREASES FIXATION, COLLAGEN MEMBRANE, DELIVERY, CELLS, OSTEONECROSIS, REGENERATION, OSTEOPOROSIS, COMPACTION, PHOSPHATE

Abstract

Purpose: To performed a histomorphometric and radiological study to evaluate the effects of alendronate sodium administered locally in mandibular bone defects created in rabbits.