Unfinished battle with childhood tuberculosis: is it curable with less drugs and shorter duration?

Cinel G., Kiper N., PEKCAN S., KOYUN M., KÖSE M., Cobanoglu N., ...More

TUBERKULOZ VE TORAK-TUBERCULOSIS AND THORAX, vol.61, no.4, pp.320-326, 2013 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 61 Issue: 4
  • Publication Date: 2013
  • Doi Number: 10.5578/tt.3890
  • Journal Name: TUBERKULOZ VE TORAK-TUBERCULOSIS AND THORAX
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.320-326
  • Keywords: Childhood tuberculosis, intermittent anti-tuberculosis treatment
  • Hacettepe University Affiliated: Yes

Abstract

Introduction: Tuberculosis is still a global health problem all over the world despite its mortality has been decreased with effective treatment regimens. Poor treatment adherence, acquired drug resistance, treatment failure and relapse are the major problems during the course of the tuberculosis treatment. Intermittent regimens have the advantages of reducing the side effects and the cost of the therapy and increasing the adherence, especially in resource-limited areas; and have been documented to be as effective as daily regimen in the paediatric population. In this study, we compared the results of 6-month and 9-month intermittent-therapy regimens with two drugs, given to the children with pulmonary and extrapulmonary tuberculosis at our hospital.