Bilateral primary breast lymphoma in a pregnant woman: a case report and literature review

YILDIRIM H. Ç., AKYILDIZ A., Ismayilov R., Demirok N., BENLİ B. S., Guven D. C., ...Daha Fazla

MEMO-MAGAZINE OF EUROPEAN MEDICAL ONCOLOGY, cilt.15, sa.4, ss.307-310, 2022 (ESCI) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 15 Sayı: 4
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1007/s12254-022-00843-4
  • Dergi Adı: MEMO-MAGAZINE OF EUROPEAN MEDICAL ONCOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, EMBASE
  • Sayfa Sayıları: ss.307-310
  • Anahtar Kelimeler: Breast, Cancer, Lymphoma, Pregnancy
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Primary breast lymphoma (PBL) represents 0.04-1% of all breast malignancies and is extremely rare in pregnancy. PBL affects women much more often than men and tends to be unilateral. Diffuse large B-cell lymphoma (DLBCL) is the most common histological subtype of PBL. Treatment options include chemotherapy, radiotherapy, immunotherapy, and surgery, but are not clearly defined. We reported herein a case of bilateral primary breast lymphoma in a 35-year-old pregnant woman. After the diagnosis of DLBCL, R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) was started in the second trimester. Postpartum intrathecal methotrexate prophylaxis and adjuvant radiotherapy were applied and a complete response was obtained. Twelve months after the initial diagnosis, our patient remains alive and relapse-free.