Vancomycin prophylaxis for revision hip arthroplasty in penicillin and cephalosporin sensitive patients: Is dose adjustment necessary in accordance with blood loss and fluid replacement?

ÇAĞLAR Ö., KAYMAKOĞLU M., Cil A., ATİLLA B., SARICAOĞLU F., Tokgozoglu M.

ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA, vol.55, no.1, pp.53-56, 2021 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 55 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.5152/j.aott.2021.20019
  • Journal Name: ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.53-56
  • Hacettepe University Affiliated: Yes

Abstract

Objective: The aims of this study were (1) to investigate the changes in the serum concentration of prophylactically administrated vancomycin in the perioperative period of revision hip arthroplasty in penicillin/cephalosporin-allergic patients. (2) to assess whether the postoperative re-administration of vancomycin is needed. and (3) to determine the relationships of vancomycin serum concentration with blood loss, body weight, and fluid replacement in such patients.