Vancomycin prophylaxis for revision hip arthroplasty in penicillin and cephalosporin sensitive patients: Is dose adjustment necessary in accordance with blood loss and fluid replacement?


ÇAĞLAR Ö. , KAYMAKOĞLU M. , Cil A. , ATİLLA B. , SARICAOĞLU F. , Tokgozoglu M.

ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA, cilt.55, sa.1, ss.53-56, 2021 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55 Konu: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5152/j.aott.2021.20019
  • Dergi Adı: ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA
  • Sayfa Sayıları: ss.53-56

Özet

Objective: The aims of this study were (1) to investigate the changes in the serum concentration of prophylactically administrated vancomycin in the perioperative period of revision hip arthroplasty in penicillin/cephalosporin-allergic patients. (2) to assess whether the postoperative re-administration of vancomycin is needed. and (3) to determine the relationships of vancomycin serum concentration with blood loss, body weight, and fluid replacement in such patients.