Hospitalization Cost in Patients with Non-convulsive Status Epilepticus: Is it Different from Other Critical Care Patients? Non-konvülsif Status Epileptikuslu Hastalarda Yatış Maliyeti: Diğer Yoğun Bakım Hastalarından Farklı mı?

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Turk Noroloji Dergisi, vol.28, no.1, pp.45-50, 2022 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.4274/tnd.2022.99233
  • Journal Name: Turk Noroloji Dergisi
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, EMBASE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.45-50
  • Keywords: Non-convulsive status epilepticus, neurological intensive care unit, health related cost, continuous EEG monitoring, REFRACTORY STATUS EPILEPTICUS, MORTALITY, EPILEPSY, BURDEN, ADULTS, EEG
  • Hacettepe University Affiliated: Yes


© 2022 by Turkish Neurological Society.Objective: Status epilepticus (SE) is one of the severe neurological emergencies with significant morbidity and mortality. Most of the time these patients require admission to intensive care units. There is little information about health-economy related burden of SE and potential factors affecting cost except for developed Western countries, especially from the perspective of non-convulsive SE (NCSE). Materials and Methods: We included all consecutive patients diagnosed as having NCSE with continuous electroencephalogram (EEG) in our neurological intensive care unit (NICU) between 2009 and 2019. Demographic and clinical features were collected from patient files. Total cost during NICU care was obtained from hospital financial records. The results were compared with other NICU patients (control group) followed during the same period for the same length of stay. We also investigated the potential impact of several parameters on cost. Results: Thirty two patients with NCSE and 32 controls were included. Mean cost per patient was 11,831 US dollars (USD) in the study and 11,240 USD in the control group (p=0.386). Increased length of stay (p<0.001), lower Glasgow Coma scale score at admission (p=0.003), and new diagnosis of NCSE after admission to NICU (p=0.018) were significantly associated with higher cost in study group. SE related direct costs (anti-seizure medicines, anesthetics and continuous EEG) comprised only 3% of total NICU care expenditures. Conclusion: Management for NCSE in NICU leads to significant intensive care related cost. The similarity of the cost level to other NICU patients indicates that most of the expenditures are related to intensive care, rather than management of seizures. We found that a few patient-related parameters could significantly affect the cost, but they were all non-modifiable.