Classical Methods and New Developments in Laboratory Diagnosis of Fungal Infections

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Gülmez Kıvanç D., Özyavuz Alp Ş.

FLORA INFEKSIYON HASTALIKLARI VE KLINIK MIKROBIYOLOJI DERGISI, vol.26, no.1, pp.34-49, 2021 (ESCI) identifier identifier


Diseases caused by fungi affect a large number of people in the world. Recently, the increase of diseases and treatment applications that suppress the immune system has caused a rise in the frequency and variety of fungal infections. This has complicated timely and definitive diagnosis and increased the need for more successful diagnostic approaches. New methods are developed especially for the diagnosis of invasive fungal infections in order to provide early and correct diagnosis and improve prognosis in vulnerable patients. For this purpose, the performances of new tests defined are evaluated in different patient groups and for different pathogens. Those found suitable are added to diagnostic algorithms. The aim of this review was to summarize the conventional and non-conventional laboratory diagnostic tests used for fungal diagnosis with their advantages and disadvantages.