Biochemical and Histopathological Effects of in Utero Di-N-Hexyl Phthalate and Di-Cyclohexyl Phthalate Exposure on the Thyroid Axes and T3, T4, TSH Hormone Levels of Male and Female Rats: at Adulthood

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Goktekin E., BARLAS N.

ERCIYES MEDICAL JOURNAL, cilt.39, sa.4, ss.176-182, 2017 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 4
  • Basım Tarihi: 2017
  • Doi Numarası: 10.5152/etd.2017.17069
  • Dergi Adı: ERCIYES MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.176-182
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Objective: To investigate the effects of di-n-hexyl phthalate (DHP) and dicyclohexyl phthalate (DCHP) on hypophysis/ thyroid axis in utero, pregnant rats were exposed to DHP or DCHP at doses of 0, 20, 100, and 500 mg/kg bw/d, by gavage, on gestational days (GD) 6-19.