Relationship between hemorheology and endothelial dysfunction in renal transplant patients receiving calcineurin inhibitors


Akoglu H. , SERINGEC N., YILDIRIM T. , YILMAZ R., Okutucu S. , Turkmen E. , ...Daha Fazla

JOURNAL OF NEPHROLOGY, cilt.26, ss.931-940, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 26 Konu: 5
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5301/jn.5000237
  • Dergi Adı: JOURNAL OF NEPHROLOGY
  • Sayfa Sayıları: ss.931-940

Özet

Background: Calcineurin inhibitors, mainly cyclosporin A (CsA), are associated with endothelial dysfunction in renal transplant recipients (RTRs). Hemorheological disturbances including decreased erythrocyte deformability (ED), increased plasma viscosity and erythrocyte aggregation (EA) have also been reported in CsA-treated RTRs. The aim of this study was to investigate the relationship between hemorheological factors and endothelial dysfunction in CsA- and tacrolimus (Tc) treated RTRs.