Relationship between hemorheology and endothelial dysfunction in renal transplant patients receiving calcineurin inhibitors

Akoglu, HADİM; SERINGEC, Nurten; YILDIRIM, TOLGA; YILMAZ, Rahmi; Okutucu, SERCAN; Turkmen, ERCAN; EVRANOS, BANU; KAYA, ERGÜN; DIKMENOGLU, NESLİHAN; ARICI, MUSTAFA; Erdem, YUNUS; TURGAN, Cetin

doi:10.5301/jn.5000237

Relationship between hemorheology and endothelial dysfunction in renal transplant patients receiving calcineurin inhibitors

Akoglu H., SERINGEC N., YILDIRIM T., YILMAZ R., Okutucu S., Turkmen E., ...Daha Fazla

JOURNAL OF NEPHROLOGY, cilt.26, sa.5, ss.931-940, 2013 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 26 Sayı: 5
Basım Tarihi: 2013
Doi Numarası: 10.5301/jn.5000237
Dergi Adı: JOURNAL OF NEPHROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.931-940
Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Calcineurin inhibitors, mainly cyclosporin A (CsA), are associated with endothelial dysfunction in renal transplant recipients (RTRs). Hemorheological disturbances including decreased erythrocyte deformability (ED), increased plasma viscosity and erythrocyte aggregation (EA) have also been reported in CsA-treated RTRs. The aim of this study was to investigate the relationship between hemorheological factors and endothelial dysfunction in CsA- and tacrolimus (Tc) treated RTRs.