Relationship between hemorheology and endothelial dysfunction in renal transplant patients receiving calcineurin inhibitors

Akoglu H., SERINGEC N., YILDIRIM T., YILMAZ R., Okutucu S., Turkmen E., ...Daha Fazla

JOURNAL OF NEPHROLOGY, cilt.26, sa.5, ss.931-940, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 5
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5301/jn.5000237
  • Dergi Adı: JOURNAL OF NEPHROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.931-940
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Calcineurin inhibitors, mainly cyclosporin A (CsA), are associated with endothelial dysfunction in renal transplant recipients (RTRs). Hemorheological disturbances including decreased erythrocyte deformability (ED), increased plasma viscosity and erythrocyte aggregation (EA) have also been reported in CsA-treated RTRs. The aim of this study was to investigate the relationship between hemorheological factors and endothelial dysfunction in CsA- and tacrolimus (Tc) treated RTRs.