Evaluation of matrix-assisted laser desorption ionization-time of flight mass spectrometry in diagnosis of clinical Nocardia species

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Hascelik G., Kostrzewa M., MÜŞTAK H. K., Uner C., DİKER K. S.

JOURNAL OF LABORATORY MEDICINE, vol.43, no.3, pp.157-162, 2019 (SCI-Expanded, Scopus)

• Publication Type: Article / Article
• Volume: 43 Issue: 3
• Publication Date: 2019
• Doi Number: 10.1515/labmed-2018-0180
• Journal Name: JOURNAL OF LABORATORY MEDICINE
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.157-162
• Open Archive Collection: AVESIS Open Access Collection
• Hacettepe University Affiliated: Yes

Abstract

Background: The routine identification to the species level of Nocardia genus by conventional methods is a fastidious and time-consuming process owing to the limited biochemical reactivity of these microorganisms, often requiring 1 or more days to complete identification. Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) is a new technology for definitive and rapid species identification.