Evaluation of Thiol Homeostasis in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders

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Arslan B., Arslan G. A., Tuncer A., KARABUDAK R., SEPİCİ DİNÇEL A.

FRONTIERS IN NEUROLOGY, vol.12, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12
  • Publication Date: 2021
  • Doi Number: 10.3389/fneur.2021.716195
  • Journal Name: FRONTIERS IN NEUROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Directory of Open Access Journals
  • Keywords: multiple sclerosis, neuromyelitis optica spectrum disease, myelin oligodendrocyte glycoprotein, thiol, oxidative stress, CELLULAR STRESS-RESPONSE, HORMETIC DOSE RESPONSES, OXIDATIVE STRESS, HORMESIS DATABASE, NERVOUS-SYSTEM, DISEASE, PLASMA, NEUROPROTECTION, PATHOGENESIS, GLUTATHIONE
  • Hacettepe University Affiliated: Yes

Abstract

Objectives: The aim of this pilot study was to evaluate dynamic thiol-disulfide homeostasis as a novel oxidative stress parameter in multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD), and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) to better understand the role of thiol homeostasis in neuroimmunological diseases.