Association of Interleukin-10 gene promoter polymorphisms with obstructive sleep apnea

Ozdas, Sibel; Ozdas, Talih; Acar, Mustafa; Erbek, Selim; Koseoglu, Sabri; Gokturk, Gokhan; İZBIRAK, AFİFE

doi:10.1007/s11325-015-1216-9

Association of Interleukin-10 gene promoter polymorphisms with obstructive sleep apnea

Ozdas S., Ozdas T., Acar M., Erbek S. S., Koseoglu S., Gokturk G., ...Daha Fazla

SLEEP AND BREATHING, cilt.20, sa.2, ss.855-866, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 20 Sayı: 2
Basım Tarihi: 2016
Doi Numarası: 10.1007/s11325-015-1216-9
Dergi Adı: SLEEP AND BREATHING
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.855-866
Hacettepe Üniversitesi Adresli: Evet

Özet

Interleukin-10 (IL) is an anti-inflammatory cytokine that regulates normal sleep patterns, and recent studies have reported that it is a potential useful biomarker to identify presence and severity of sleep apnea syndrome (OSAS). Promoter polymorphisms of IL-10 gene have been associated with altered expression levels, which contributes to OSAS.