Association of Interleukin-10 gene promoter polymorphisms with obstructive sleep apnea
SLEEP AND BREATHING, vol.20, no.2, pp.855-866, 2016 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 20 Issue: 2
- Publication Date: 2016
- Doi Number: 10.1007/s11325-015-1216-9
- Journal Name: SLEEP AND BREATHING
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.855-866
- Hacettepe University Affiliated: Yes
Abstract
Interleukin-10 (IL) is an anti-inflammatory cytokine that regulates normal sleep patterns, and recent studies have reported that it is a potential useful biomarker to identify presence and severity of sleep apnea syndrome (OSAS). Promoter polymorphisms of IL-10 gene have been associated with altered expression levels, which contributes to OSAS.