Association of Interleukin-10 gene promoter polymorphisms with obstructive sleep apnea

Ozdas S., Ozdas T., Acar M., Erbek S. S., Koseoglu S., Gokturk G., ...More

SLEEP AND BREATHING, vol.20, no.2, pp.855-866, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.1007/s11325-015-1216-9
  • Journal Name: SLEEP AND BREATHING
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.855-866
  • Hacettepe University Affiliated: Yes

Abstract

Interleukin-10 (IL) is an anti-inflammatory cytokine that regulates normal sleep patterns, and recent studies have reported that it is a potential useful biomarker to identify presence and severity of sleep apnea syndrome (OSAS). Promoter polymorphisms of IL-10 gene have been associated with altered expression levels, which contributes to OSAS.