Comparative Effectiveness of Botulinum Toxin Injections and Extracorporeal Shockwave Therapy for Post-Stroke Spasticity: A Systematic Review and Network Meta-Analysis

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Hsu P., Chang K., Chiu Y., Wu W., ÖZÇAKAR L.

ECLINICALMEDICINE, vol.43, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 43
  • Publication Date: 2022
  • Doi Number: 10.1016/j.eclinm.2021.101222
  • Journal Name: ECLINICALMEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Directory of Open Access Journals
  • Keywords: chemodenervation, radial shockwave, focused shockwave, hemiplegia, hypertonia, UPPER-LIMB SPASTICITY, WAVE THERAPY, DOUBLE-BLIND, CHRONIC STROKE, SHOULDER PAIN, CEREBRAL-PALSY, PLACEBO, STIMULATION, PATHOPHYSIOLOGY, DISABILITY
  • Hacettepe University Affiliated: Yes

Abstract

Background The anti-spasticity efficacy of botulinum toxin (BoNT) injection has been well established for patients with chronic stroke; however, extracorporeal shock wave therapy (ESWT), i.e. focused shockwave (FSW) and radial shockwave (RSW), has recently been applied. We aimed to investigate the comparative effectiveness of BoNT vs. ESWT in the reduction of spasticity among stroke survivors.