The effect of polymorphisms at the CD14 promoter and the TLR4 gene on asthma phenotypes in Turkish children with asthma.


Sackesen C. , Karaaslan C. , KESKİN Ö., TOKOL N., TAHAN F., Civelek E. , ...Daha Fazla

Allergy, cilt.60, ss.1485-92, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Background: Endotoxin, with its potential to enhance type 1 immunity, is a significant player in the hygiene hypothesis. The combined effects of the genetic variants of various molecules in the endotoxin response pathway on asthma related phenotypes are largely unknown.