The effect of polymorphisms at the CD14 promoter and the TLR4 gene on asthma phenotypes in Turkish children with asthma.

Sackesen C., Karaaslan C., KESKİN Ö., TOKOL N., TAHAN F., Civelek E., ...More

Allergy, vol.60, no.12, pp.1485-92, 2005 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 60 Issue: 12
  • Publication Date: 2005
  • Doi Number: 10.1111/j.1398-9995.2005.00874.x
  • Journal Name: Allergy
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.1485-92


Background: Endotoxin, with its potential to enhance type 1 immunity, is a significant player in the hygiene hypothesis. The combined effects of the genetic variants of various molecules in the endotoxin response pathway on asthma related phenotypes are largely unknown.