Delusions and/or hallucinations developed during exposure to a medication are diagnosed medication induced psychotic disorder. Antibiotic-induced psychotic disorder have been well documented among adults. The etiology is not clear, clinical presentation is variable and catatonia-like symptoms can be seen. The prognosis is good, the symptoms decrease with the discontination of the drug, and long-term treatment is often not required. In this case, 16-year-old girl who presented with acute catatonia-like symptoms will be described. Family history of clarithromycin-induced behaviour changes accelerated the diagnosis process. Medication induced psychotic disorder should be thought in differential diagnosis of young people with acute psyhotic symptoms.