JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, vol.144, no.6, pp.997-1003, 2018 (Journal Indexed in SCI)
Article / Review
Title of Journal :
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
Immunotherapy, Lung cancer, Natural killer cells, Non-small cell lung cancer, Small cell lung cancer, NK CELLS, CIGARETTE-SMOKE, T-CELLS, ADOPTIVE IMMUNOTHERAPY, MEDIATED CYTOTOXICITY, IMMUNE RESPONSIVENESS, PERIPHERAL-BLOOD, DENDRITIC CELLS, MOUSE MODEL, EXPRESSION
Purpose One of the key immune cells involved in the pathogenesis of lung cancer is natural killer (NK) cells and these cells are novel targets for therapeutic applications in lung cancer. The purpose of this review is to summarize the current literature on lung cancer pathogenesis with a focus on the interaction between NK cells and smoking, how these factors are related to the pathogenesis of lung cancer and how NK cell-based immunotherapy effect lung cancer survival.