Role of natural killer cells in lung cancer


Aktas O. N. , Ozturk A. B. , Erman B. , Erus S., Tanju S., Dilege S.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, cilt.144, ss.997-1003, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 144 Konu: 6
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1007/s00432-018-2635-3
  • Dergi Adı: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
  • Sayfa Sayıları: ss.997-1003

Özet

Purpose One of the key immune cells involved in the pathogenesis of lung cancer is natural killer (NK) cells and these cells are novel targets for therapeutic applications in lung cancer. The purpose of this review is to summarize the current literature on lung cancer pathogenesis with a focus on the interaction between NK cells and smoking, how these factors are related to the pathogenesis of lung cancer and how NK cell-based immunotherapy effect lung cancer survival.