Synchrotron FT-IR microspectroscopic analysis of necrotic bone

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Bayari S. H., UTKU H., IKEMOTO Y., Celasun B., Koemuercue M., ATIK A.

SPECTROSCOPY-AN INTERNATIONAL JOURNAL, vol.21, no.4, pp.227-234, 2007 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 21 Issue: 4
  • Publication Date: 2007
  • Doi Number: 10.1155/2007/732013
  • Journal Name: SPECTROSCOPY-AN INTERNATIONAL JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.227-234
  • Keywords: avascular necrosis, necrotic bone, synchrotron, FT-IR microspectroscopy, TRANSFORM INFRARED-SPECTROSCOPY, ILIAC CREST BIOPSIES, MICRO-SPECTROSCOPY, CALCIUM-PHOSPHATE, MINERAL-CONTENT, HYDROXYAPATITE, CRYSTALLINITY, OVARIECTOMY, TIBIA
  • Open Archive Collection: AVESIS Open Access Collection
  • Hacettepe University Affiliated: Yes

Abstract

Avascular necrosis (osteonecrosis) is a disease that results from the temporary or permanent loss of blood supply to the bone. Synchrotron FT-IR microspectroscopy has been used to study the changes in mineral and matrix content of necrotic bone. FT-IR spectroscopic analysis revealed that in necrotic bone the relative mineral/matrix ratio decreased. Spectroscopic differences were observed between normal and necrotic bones. The noticeable differences may have important implications for analyzing and evaluating death bone.