Synchrotron FT-IR microspectroscopic analysis of necrotic bone

Bayari S. H. , UTKU H. , IKEMOTO Y., Celasun B., Koemuercue M., ATIK A.

SPECTROSCOPY-AN INTERNATIONAL JOURNAL, cilt.21, ss.227-234, 2007 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 21 Konu: 4
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1155/2007/732013
  • Sayfa Sayıları: ss.227-234


Avascular necrosis (osteonecrosis) is a disease that results from the temporary or permanent loss of blood supply to the bone. Synchrotron FT-IR microspectroscopy has been used to study the changes in mineral and matrix content of necrotic bone. FT-IR spectroscopic analysis revealed that in necrotic bone the relative mineral/matrix ratio decreased. Spectroscopic differences were observed between normal and necrotic bones. The noticeable differences may have important implications for analyzing and evaluating death bone.