The effects of selective nitric oxide synthase blocker on survival, mesenteric blood flow and multiple organ failure induced by zymosan

Tanriverdi, P; Yuksel, BC; Rasa, K; Guler, GÜLNUR; Iskit, AB; Guc, MO; Korkmaz, A

doi:10.1016/j.jss.2004.09.004

The effects of selective nitric oxide synthase blocker on survival, mesenteric blood flow and multiple organ failure induced by zymosan

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Tanriverdi P., Yuksel B., Rasa K., Guler G., Iskit A., Guc M., ...More

JOURNAL OF SURGICAL RESEARCH, vol.124, no.1, pp.67-73, 2005 (SCI-Expanded)

Publication Type: Article / Article
Volume: 124 Issue: 1
Publication Date: 2005
Doi Number: 10.1016/j.jss.2004.09.004
Journal Name: JOURNAL OF SURGICAL RESEARCH
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.67-73
Hacettepe University Affiliated: Yes

Abstract

Background. Circulatory failure in multiple organ dysfunction syndromes (MODS) is characterized with systemic vasodilation, diminished blood flow to various vascular beds. The aim of this study was to investigate the effects of selective inhibition of nitric oxide on the mesenteric arterial blood flow (MABF), survival and organ injury of the liver, kidney, lung and spleen in zymosan-induced MODS.