The Correlation Between Reactive Oxygen Species and Histopathology of the Liver, Gut, and Kidneys in Animals with Elevated Intra-abdominal Pressure


Ozmen M. M. , Zulfikaroglu B., Besler T. H. , Col C., Cinel L., Cinel I.

JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES, cilt.19, ss.339-343, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 19 Konu: 3
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1089/lap.2008.0293
  • Dergi Adı: JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES
  • Sayfa Sayıları: ss.339-343

Özet

Background: Clinical and experimental studies have shown that the laparoscopic procedure provides a typical model of ischemia-reperfusion injury in the organs by oxygen-derived free radicals. A pneumoperitoneum produces ischemia during insufflation and reperfusion during desufflation. The aim of this study was to assess the causative role of free radical-mediated reactions in tissue damage under different intra-abdominal insufflation pressures.