The Therapeutic Effects of Melatonin and Nimodipine in Rats after Cerebral Cortical Injury

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İSMAİLOĞLU Ö., ATİLLA P., Palaoglu S., Cakar N., YAŞAR Ü., Kilinc K., ...Daha Fazla

TURKISH NEUROSURGERY, cilt.22, sa.6, ss.740-746, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.5137/1019-5149.jtn.6197-12.1
  • Dergi Adı: TURKISH NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.740-746
  • Anahtar Kelimeler: Melatonin, Nimodipine, Head trauma, Rat, SPONTANEOUSLY HYPERTENSIVE RATS, BRAIN-INJURY, LIPID-PEROXIDATION, SUBARACHNOID HEMORRHAGE, HEAD TRAUMA, ISCHEMIA, ANTAGONISTS, EDEMA, TRIAL
  • Hacettepe Üniversitesi Adresli: Evet

Özet

AIM: Secondary brain injury starts after the initial traumatic impact and marked by an increase in the intracellular calcium concentrations. This cascadeeventually results in membrane lipid peroxidation and neuronal cell death.