The Therapeutic Effects of Melatonin and Nimodipine in Rats after Cerebral Cortical Injury

Creative Commons License

İSMAİLOĞLU Ö., ATİLLA P., Palaoglu S., Cakar N., YAŞAR Ü., Kilinc K., ...More

TURKISH NEUROSURGERY, vol.22, no.6, pp.740-746, 2012 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 6
  • Publication Date: 2012
  • Doi Number: 10.5137/1019-5149.jtn.6197-12.1
  • Journal Name: TURKISH NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.740-746
  • Keywords: Melatonin, Nimodipine, Head trauma, Rat, SPONTANEOUSLY HYPERTENSIVE RATS, BRAIN-INJURY, LIPID-PEROXIDATION, SUBARACHNOID HEMORRHAGE, HEAD TRAUMA, ISCHEMIA, ANTAGONISTS, EDEMA, TRIAL
  • Hacettepe University Affiliated: Yes

Abstract

AIM: Secondary brain injury starts after the initial traumatic impact and marked by an increase in the intracellular calcium concentrations. This cascadeeventually results in membrane lipid peroxidation and neuronal cell death.