Highly Selective Benzo[a]Pyrene Detection Even under Competitive Conditions with Molecularly Imprinted Surface Plasmon Resonance Sensor
POLYCYCLIC AROMATIC COMPOUNDS, cilt.43, sa.5, ss.3896-3909, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 43 Sayı: 5
- Basım Tarihi: 2023
- Doi Numarası: 10.1080/10406638.2022.2080725
- Dergi Adı: POLYCYCLIC AROMATIC COMPOUNDS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Applied Science & Technology Source, CAB Abstracts, Chemical Abstracts Core, Communication Abstracts, Food Science & Technology Abstracts, Metadex, Pollution Abstracts, Veterinary Science Database, Civil Engineering Abstracts
- Sayfa Sayıları: ss.3896-3909
- Anahtar Kelimeler: Surface plasmon resonance, molecularly imprinted polymers, benzo[a]pyrene, polyaromatic hydrocarbons, N-methacryloyl-L-phenylalanine, POLYCYCLIC AROMATIC-HYDROCARBONS, PER-TRILLION LEVELS, ORAL-EXPOSURE, BENZO(A)PYRENE, ENHANCEMENT, POLLUTANTS, POLYMERS, BAP
- Hacettepe Üniversitesi Adresli: Evet
Özet
In this study, a new approach for the detection of benzo[a]pyrene (BaP) in aqueous media is presented by combining molecularly imprinted polymers (MIPs) with surface plasmon resonance (SPR) sensors. Herein, BaP imprinted sensor was fabricated on a SPR chip in the presence of a pre-polymerization complex of BaP and N-methacryloyl-L-phenylalanine, 2-hydroxyethyl methacrylate (HEMA), and ethylene glycol dimethacrylate (EGDMA). The developed sensor was characterized by atomic force microscopy, ellipsometry, and contact angle measurements. Association kinetics analysis via Scatchard, Langmuir, Freundlich, Langmuir-Freundlich isotherms were applied to the data and Langmuir adsorption model was found as the most accurate model for the affinity sensor system. MIPs-based SPR sensor linearly responded to BaP in a concentration range of 20-400 ng mL(-1) with an excellent LOD of 14.97 ng L-1. The SPR sensor was found to be highly selective toward BaP according to the selectivity study results in the presence of interfering agents such as benzo[b]floranthene (BbF), benzo[k]floranthene (BkF), indeno[1,2,3-cd]pyrene (IcdP), and 1-naphthol. The studies demonstrated that MIPs-based SPR sensor provides rapid and reliable detection and identification of polyaromatic hydrocarbons (PAHs) within a quite short time.