Highly Selective Benzo[a]Pyrene Detection Even under Competitive Conditions with Molecularly Imprinted Surface Plasmon Resonance Sensor


Corman M. E., ARMUTCU ÇORMAN C., Karasu T., ÖZGÜR E., UZUN L.

POLYCYCLIC AROMATIC COMPOUNDS, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Publication Date: 2022
  • Doi Number: 10.1080/10406638.2022.2080725
  • Journal Name: POLYCYCLIC AROMATIC COMPOUNDS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Applied Science & Technology Source, CAB Abstracts, Chemical Abstracts Core, Communication Abstracts, Food Science & Technology Abstracts, Metadex, Pollution Abstracts, Veterinary Science Database, Civil Engineering Abstracts
  • Keywords: Surface plasmon resonance, molecularly imprinted polymers, benzo[a]pyrene, polyaromatic hydrocarbons, N-methacryloyl-L-phenylalanine, POLYCYCLIC AROMATIC-HYDROCARBONS, PER-TRILLION LEVELS, ORAL-EXPOSURE, BENZO(A)PYRENE, ENHANCEMENT, POLLUTANTS, POLYMERS, BAP
  • Hacettepe University Affiliated: Yes

Abstract

In this study, a new approach for the detection of benzo[a]pyrene (BaP) in aqueous media is presented by combining molecularly imprinted polymers (MIPs) with surface plasmon resonance (SPR) sensors. Herein, BaP imprinted sensor was fabricated on a SPR chip in the presence of a pre-polymerization complex of BaP and N-methacryloyl-L-phenylalanine, 2-hydroxyethyl methacrylate (HEMA), and ethylene glycol dimethacrylate (EGDMA). The developed sensor was characterized by atomic force microscopy, ellipsometry, and contact angle measurements. Association kinetics analysis via Scatchard, Langmuir, Freundlich, Langmuir-Freundlich isotherms were applied to the data and Langmuir adsorption model was found as the most accurate model for the affinity sensor system. MIPs-based SPR sensor linearly responded to BaP in a concentration range of 20-400 ng mL(-1) with an excellent LOD of 14.97 ng L-1. The SPR sensor was found to be highly selective toward BaP according to the selectivity study results in the presence of interfering agents such as benzo[b]floranthene (BbF), benzo[k]floranthene (BkF), indeno[1,2,3-cd]pyrene (IcdP), and 1-naphthol. The studies demonstrated that MIPs-based SPR sensor provides rapid and reliable detection and identification of polyaromatic hydrocarbons (PAHs) within a quite short time.