Radiation sterilization of new drug delivery systems
INTERVENTIONAL MEDICINE AND APPLIED SCIENCE, vol.6, no.2, pp.51-60, 2014 (ESCI, Scopus)
- Publication Type: Article / Review
- Volume: 6 Issue: 2
- Publication Date: 2014
- Doi Number: 10.1556/imas.6.2014.2.1
- Journal Name: INTERVENTIONAL MEDICINE AND APPLIED SCIENCE
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
- Page Numbers: pp.51-60
- Hacettepe University Affiliated: Yes
Abstract
Radiation sterilization has now become a commonly used method for sterilization of several active ingredients in drugs or drug delivery systems containing these substances. In this context, many applications have been performed on the human products that are required to be sterile, as well as on pharmaceutical products prepared to be developed. The new drug delivery systems designed to deliver the medication to the target tissue or organ, such as microspheres, nanospheres, microemulsion, and liposomal systems, have been sterilized by gamma (gamma) and beta (beta) rays, and more recently, by e-beam sterilization. In this review, the sterilization of new drug delivery systems was discussed other than conventional drug delivery systems by. irradiation.