6-[3-Phenyl-5-(trifluoromethyl)pyrazol-1-yl]-pyridazin-3(2H)-one

Dilek, N; Gunes, B; Sahin, E; Ide, SEMRA; Unlum, S

doi:10.1107/s160053680504256x

6-[3-Phenyl-5-(trifluoromethyl)pyrazol-1-yl]-pyridazin-3(2H)-one

Dilek N., Gunes B., Sahin E., Ide S., Unlum S.

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, vol.62, 2006 (SCI-Expanded, ESCI, Scopus)

Publication Type: Article / Article
Volume: 62
Publication Date: 2006
Doi Number: 10.1107/s160053680504256x
Journal Name: ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Emerging Sources Citation Index (ESCI), Scopus
Hacettepe University Affiliated: Yes

Abstract

This study of the title compound, C14H9F3N4O, is part of a series of structural investigations of cyclooxygenase-2 (COX-2) inhibitors containing 1,3-diarylpyrazole derivatives. The crystal structure is stabilized by intermolecular N-H center dot center dot center dot O and C-H center dot center dot center dot F hydrogen-bonding interactions.